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Structural characterization of Class 2 OLD family nucleases supports a two-metal catalysis mechanism for cleavage
Overcoming lysogenization defect (OLD) proteins constitute a family of uncharacterized nucleases present in bacteria, archaea, and some viruses. These enzymes contain an N-terminal ATPase domain and a C-terminal Toprim domain common amongst replication, recombination, and repair proteins. The in viv...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755086/ https://www.ncbi.nlm.nih.gov/pubmed/31400118 http://dx.doi.org/10.1093/nar/gkz703 |