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DNA polymerase activity on synthetic N3′→P5′ phosphoramidate DNA templates

Genetic polymers that could plausibly govern life in the universe might inhabit a broad swath of chemical space. A subset of these genetic systems can exchange information with RNA and DNA and could therefore form the basis for model protocells in the laboratory. N3′→P5′ phosphoramidate (NP) DNA is...

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Detalles Bibliográficos
Autores principales: Lelyveld, Victor S, O’Flaherty, Derek K, Zhou, Lijun, Izgu, Enver Cagri, Szostak, Jack W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755091/
https://www.ncbi.nlm.nih.gov/pubmed/31428779
http://dx.doi.org/10.1093/nar/gkz707