Impacts of uORF codon identity and position on translation regulation

Translation regulation plays an important role in eukaryotic gene expression. Upstream open reading frames (uORFs) are potent regulatory elements located in 5′ mRNA transcript leaders. Translation of uORFs usually inhibit the translation of downstream main open reading frames, but some enhance expre...

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Detalles Bibliográficos
Autores principales: Lin, Yizhu, May, Gemma E, Kready, Hunter, Nazzaro, Lauren, Mao, Mao, Spealman, Pieter, Creeger, Yehuda, McManus, C Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755093/
https://www.ncbi.nlm.nih.gov/pubmed/31392980
http://dx.doi.org/10.1093/nar/gkz681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755093/
https://www.ncbi.nlm.nih.gov/pubmed/31392980
http://dx.doi.org/10.1093/nar/gkz681

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