Bacillus subtilis RecA interacts with and loads RadA/Sms to unwind recombination intermediates during natural chromosomal transformation

During natural transformation Bacillus subtilis RecA, polymerized onto the incoming single-stranded (ss) DNA, catalyses DNA strand invasion resulting in a displacement loop (D-loop) intermediate. A null radA mutation impairs chromosomal transformation, and RadA/Sms unwinds forked DNA in the 5′→3′ di...

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Detalles Bibliográficos
Autores principales: Torres, Rubén, Serrano, Ester, Alonso, Juan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755099/
https://www.ncbi.nlm.nih.gov/pubmed/31350886
http://dx.doi.org/10.1093/nar/gkz647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755099/
https://www.ncbi.nlm.nih.gov/pubmed/31350886
http://dx.doi.org/10.1093/nar/gkz647

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