eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons

Codon usage bias is a universal feature of eukaryotic and prokaryotic genomes and plays an important role in regulating gene expression levels. A major role of codon usage is thought to regulate protein expression levels by affecting mRNA translation efficiency, but the underlying mechanism is uncle...

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Detalles Bibliográficos
Autores principales: Yang, Qian, Yu, Chien-Hung, Zhao, Fangzhou, Dang, Yunkun, Wu, Cheng, Xie, Pancheng, Sachs, Matthew S, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755126/
https://www.ncbi.nlm.nih.gov/pubmed/31410471
http://dx.doi.org/10.1093/nar/gkz710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755126/
https://www.ncbi.nlm.nih.gov/pubmed/31410471
http://dx.doi.org/10.1093/nar/gkz710

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