Cargando…

eRF1 mediates codon usage effects on mRNA translation efficiency through premature termination at rare codons

Codon usage bias is a universal feature of eukaryotic and prokaryotic genomes and plays an important role in regulating gene expression levels. A major role of codon usage is thought to regulate protein expression levels by affecting mRNA translation efficiency, but the underlying mechanism is uncle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Qian, Yu, Chien-Hung, Zhao, Fangzhou, Dang, Yunkun, Wu, Cheng, Xie, Pancheng, Sachs, Matthew S, Liu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755126/ https://www.ncbi.nlm.nih.gov/pubmed/31410471 http://dx.doi.org/10.1093/nar/gkz710

Ejemplares similares

Effect of small molecule eRF3 degraders on premature termination codon readthrough
por: Baradaran-Heravi, Alireza, et al.
Publicado: (2021)

Adenine and guanine recognition of stop codon is mediated by different N domain conformations of translation termination factor eRF1
por: Bulygin, Konstantin N., et al.
Publicado: (2011)

Codon usage biases co-evolve with transcription termination machinery to suppress premature cleavage and polyadenylation
por: Zhou, Zhipeng, et al.
Publicado: (2018)

A single amino acid change of translation termination factor eRF1 switches between bipotent and omnipotent stop-codon specificity(†)
por: Eliseev, Boris, et al.
Publicado: (2011)

Misdecoding of rare CGA codon by translation termination factors, eRF1/eRF3, suggests novel class of ribosome rescue pathway in S. cerevisiae
por: Wada, Miki, et al.
Publicado: (2018)

Two-step model of stop codon recognition by eukaryotic release factor eRF1
por: Kryuchkova, Polina, et al.
Publicado: (2013)

Small-molecule eRF3a degraders rescue CFTR nonsense mutations by promoting premature termination codon readthrough
por: Lee, Rhianna E., et al.
Publicado: (2022)

Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1
por: Wong, Leo E., et al.
Publicado: (2012)

Codon usage and protein length-dependent feedback from translation elongation regulates translation initiation and elongation speed
por: Lyu, Xueliang, et al.
Publicado: (2021)

New insights into stop codon recognition by eRF1
por: Blanchet, Sandra, et al.
Publicado: (2015)

Termination of translation in eukaryotes is mediated by the quaternary eRF1•eRF3•GTP•Mg(2+) complex. The biological roles of eRF3 and prokaryotic RF3 are profoundly distinct
por: Mitkevich, Vladimir A., et al.
Publicado: (2006)

Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells
por: Zhao, Fangzhou, et al.
Publicado: (2017)

Analysis of computational codon usage models and their association with translationally slow codons
por: Wright, Gabriel, et al.
Publicado: (2020)

A genetic approach for analyzing the co-operative function of the tRNA mimicry complex, eRF1/eRF3, in translation termination on the ribosome
por: Wada, Miki, et al.
Publicado: (2014)

Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape
por: Lyu, Xueliang, et al.
Publicado: (2020)

Mutation at Tyrosine in AMLRY (GILRY Like) Motif of Yeast eRF1 on Nonsense Codons Suppression and Binding Affinity to eRF3
por: Akhmaloka,, et al.
Publicado: (2008)

Premature termination codons in modern human genomes
por: Fujikura, Kohei
Publicado: (2016)

PABP enhances release factor recruitment and stop codon recognition during translation termination
por: Ivanov, Alexandr, et al.
Publicado: (2016)

Genetic analysis of L123 of the tRNA-mimicking eukaryote release factor eRF1, an amino acid residue critical for discrimination of stop codons
por: Saito, Kazuki, et al.
Publicado: (2015)

Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3
por: Beißel, Christian, et al.
Publicado: (2019)

N-terminal region of Saccharomyces cerevisiae eRF3 is essential for the functioning of the eRF1/eRF3 complex beyond translation termination
por: Urakov, Valery N, et al.
Publicado: (2006)

Selection for efficient translation initiation biases codon usage at second amino acid position in secretory proteins
por: Zalucki, Yaramah M., et al.
Publicado: (2007)

Modal Codon Usage: Assessing the Typical Codon Usage of a Genome
por: Davis, James J., et al.
Publicado: (2010)

Codon-by-Codon Modulation of Translational Speed and Accuracy Via mRNA Folding
por: Yang, Jian-Rong, et al.
Publicado: (2014)

Codon usage and codon context bias in Xanthophyllomyces dendrorhous
por: Baeza, Marcelo, et al.
Publicado: (2015)

The role of nucleotide composition in premature termination codon recognition
por: Zahdeh, Fouad, et al.
Publicado: (2016)

Engineered transfer RNAs for suppression of premature termination codons
por: Lueck, John D., et al.
Publicado: (2019)

GTP-dependent structural rearrangement of the eRF1:eRF3 complex and eRF3 sequence motifs essential for PABP binding
por: Kononenko, Artem V., et al.
Publicado: (2010)

Codon usage bias
por: Parvathy, Sujatha Thankeswaran, et al.
Publicado: (2021)

ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons
por: Serdar, Lucas D., et al.
Publicado: (2016)

Advances in therapeutic use of a drug-stimulated translational readthrough of premature termination codons
por: Dabrowski, Maciej, et al.
Publicado: (2018)

Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing eRF1-eRF3 or eRF1-ABCE1
por: Preis, Anne, et al.
Publicado: (2014)

Structural characterization of eRF1 mutants indicate a complex mechanism of stop codon recognition
por: Pillay, Shubhadra, et al.
Publicado: (2016)

On finding poorly translated codons based on their usage frequency
por: Ponnala, Lalit
Publicado: (2009)

Balanced Codon Usage Optimizes Eukaryotic Translational Efficiency
por: Qian, Wenfeng, et al.
Publicado: (2012)

Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
por: Krüger, Annika, et al.
Publicado: (2023)

The Dynamic Codon Biaser: calculating prokaryotic codon usage biases
por: Dehlinger, Brian, et al.
Publicado: (2021)

The Codon Statistics Database: A Database of Codon Usage Bias
por: Subramanian, Krishnamurthy, et al.
Publicado: (2022)

COUSIN (COdon Usage Similarity INdex): A Normalized Measure of Codon Usage Preferences
por: Bourret, Jérôme, et al.
Publicado: (2019)

Genome-wide analysis of chimpanzee genes with premature termination codons
por: Wetterbom, Anna, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_bljfugvflh7lt6ecud4v03p44v