MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12

Osteoporosis deteriorates bone mass and biomechanical strength, becoming a life-threatening cause to the elderly. MicroRNA is known to regulate tissue remodeling; however, its role in the development of osteoporosis remains elusive. In this study, we uncovered that silencing miR-29a expression decre...

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Detalles Bibliográficos
Autores principales: Lian, Wei-Shiung, Ko, Jih-Yang, Chen, Yu-Shan, Ke, Huei-Jing, Hsieh, Chin-Kuei, Kuo, Chung-Wen, Wang, Shao-Yu, Huang, Bo-Wun, Tseng, Jung-Ge, Wang, Feng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755134/
https://www.ncbi.nlm.nih.gov/pubmed/31543513
http://dx.doi.org/10.1038/s41419-019-1942-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755134/
https://www.ncbi.nlm.nih.gov/pubmed/31543513
http://dx.doi.org/10.1038/s41419-019-1942-1

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