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MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12
Osteoporosis deteriorates bone mass and biomechanical strength, becoming a life-threatening cause to the elderly. MicroRNA is known to regulate tissue remodeling; however, its role in the development of osteoporosis remains elusive. In this study, we uncovered that silencing miR-29a expression decre...
Autores principales: | Lian, Wei-Shiung, Ko, Jih-Yang, Chen, Yu-Shan, Ke, Huei-Jing, Hsieh, Chin-Kuei, Kuo, Chung-Wen, Wang, Shao-Yu, Huang, Bo-Wun, Tseng, Jung-Ge, Wang, Feng-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755134/ https://www.ncbi.nlm.nih.gov/pubmed/31543513 http://dx.doi.org/10.1038/s41419-019-1942-1 |
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