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Sam68 mediates high glucose-induced podocyte apoptosis through modulation of Bax/Bcl-2

Hyperglycemia promotes podocyte apoptosis and contributes to the pathogenesis of diabetic nephropathy (DN). However, the mechanisms of hyperglycemia-induced podocyte apoptosis remain unknown. Recent studies have implicated Src-associated substrate during mitosis of 68 kDa (Sam68) in various cellular...

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Detalles Bibliográficos
Autores principales: Chen, Yuyu, Zhang, Li, Liu, Shuangxin, Yao, Binfeng, Zhang, Hong, Liang, Shun, Ma, Jianchao, Liang, Xinling, Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755155/
https://www.ncbi.nlm.nih.gov/pubmed/31485651
http://dx.doi.org/10.3892/mmr.2019.10601