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Sam68 mediates high glucose-induced podocyte apoptosis through modulation of Bax/Bcl-2
Hyperglycemia promotes podocyte apoptosis and contributes to the pathogenesis of diabetic nephropathy (DN). However, the mechanisms of hyperglycemia-induced podocyte apoptosis remain unknown. Recent studies have implicated Src-associated substrate during mitosis of 68 kDa (Sam68) in various cellular...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755155/ https://www.ncbi.nlm.nih.gov/pubmed/31485651 http://dx.doi.org/10.3892/mmr.2019.10601 |