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Rapamycin improves sevoflurane-induced cognitive dysfunction in aged rats by mediating autophagy through the TLR4/MyD88/NF-κB signaling pathway

The present study was aimed to observe the protective effect of rapamycin on cognitive dysfunction induced by sevoflurane in aged rats and its effect on autophagy-related proteins, and to investigate the regulatory mechanism of the Toll-like receptor 4/myeloid differentiation primary response 88/nuc...

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Detalles Bibliográficos
Autores principales: Li, Yan, Liu, Lidan, Tian, Yue, Zhang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755174/
https://www.ncbi.nlm.nih.gov/pubmed/31432123
http://dx.doi.org/10.3892/mmr.2019.10541