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p27(kip1) haploinsufficiency preserves myocardial function in the early stages of myocardial infarction via Atg5-mediated autophagy flux restoration
Myocardial infarction (MI) is a leading cause of mortality in adults worldwide. Over the last two decades, gene therapy has been a hot topic in cardiology, and there has been a focus on cell cycle inhibitors and their protective effects on the myocardium post-MI. In our previous study, the haploinsu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755177/ https://www.ncbi.nlm.nih.gov/pubmed/31485654 http://dx.doi.org/10.3892/mmr.2019.10632 |