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p27(kip1) haploinsufficiency preserves myocardial function in the early stages of myocardial infarction via Atg5-mediated autophagy flux restoration

Myocardial infarction (MI) is a leading cause of mortality in adults worldwide. Over the last two decades, gene therapy has been a hot topic in cardiology, and there has been a focus on cell cycle inhibitors and their protective effects on the myocardium post-MI. In our previous study, the haploinsu...

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Detalles Bibliográficos
Autores principales: Zhou, Ningtian, Huang, Qiong, Cheng, Weili, Ge, Yingbin, Li, Dianfu, Wang, Junhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755177/
https://www.ncbi.nlm.nih.gov/pubmed/31485654
http://dx.doi.org/10.3892/mmr.2019.10632