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Lentiviral-mediated Shh reverses the adverse effects of high glucose on osteoblast function and promotes bone formation via Sonic hedgehog signaling

Patients with diabetes tend to have an increased incidence of osteoporosis, which may be associated with hyperglycemia; however, the pathogenic mechanisms governing this interaction remain unknown. The present study sought to investigate whether elevated extracellular glucose levels of bone mesenchy...

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Detalles Bibliográficos
Autores principales: Jiang, Zhu-Ling, Jin, Han, Liu, Zhong-Shuang, Liu, Ming-Yue, Cao, Xiao-Fang, Jiang, Yang-Yang, Bai, Hong-Dan, Zhang, Bin, Li, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755203/
https://www.ncbi.nlm.nih.gov/pubmed/31432117
http://dx.doi.org/10.3892/mmr.2019.10540