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Apolipoprotein E-Mimetic Peptide COG1410 Enhances Retinal Ganglion Cell Survival by Attenuating Inflammation and Apoptosis Following TONI

Vision loss after traumatic optic nerve injury (TONI) is considered irreversible because of the retrograde loss of retinal ganglion cells (RGCs), which undergo inflammation and apoptosis. Previous studies have shown that COG1410, a mimic peptide derived from the apolipoprotein E (apoE) receptor bind...

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Detalles Bibliográficos
Autores principales: Kuai, Li, Peng, Jianhua, Jiang, Yong, Zheng, Zheng, Zhou, Xiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755331/
https://www.ncbi.nlm.nih.gov/pubmed/31607842
http://dx.doi.org/10.3389/fnins.2019.00980