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Fractalkine Modulates Microglia Metabolism in Brain Ischemia

In the CNS, the chemokine CX3CL1 (fractalkine) is expressed on neurons while its specific receptor CX3CR1 is expressed on microglia and macrophages. Microglia play an important role in health and disease through CX3CL1/CX3CR1 signaling, and in many neurodegenerative disorders, microglia dysregulatio...

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Detalles Bibliográficos
Autores principales: Lauro, Clotilde, Chece, Giuseppina, Monaco, Lucia, Antonangeli, Fabrizio, Peruzzi, Giovanna, Rinaldo, Serena, Paone, Alessio, Cutruzzolà, Francesca, Limatola, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755341/
https://www.ncbi.nlm.nih.gov/pubmed/31607865
http://dx.doi.org/10.3389/fncel.2019.00414