Gene delivery into hepatic cells with ternary complexes of plasmid DNA, cationic liposomes and apolipoprotein E-derived peptide

Cationic liposomes containing a cationic lipid, such as 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP), have often been used for the transduction of plasmid DNA (pDNA) in vivo. However, such liposomes induce gene expression primarily in the lungs after intravenous injection. To improve the deliver...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshiyuki, Nakagawa, Yuta, Onishi, Hiraku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755467/
https://www.ncbi.nlm.nih.gov/pubmed/31572511
http://dx.doi.org/10.3892/etm.2019.7863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755467/
https://www.ncbi.nlm.nih.gov/pubmed/31572511
http://dx.doi.org/10.3892/etm.2019.7863

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