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MicroRNA-146a inhibits NF-κB activation and pro-inflammatory cytokine production by regulating IRAK1 expression in THP-1 cells

MicroRNA (miR)-146a levels are reduced in peripheral blood mononuclear cells of patients with systemic lupus erythematosus (SLE); however, its function is not well understood. The present study investigated the role of miR-146a in the regulation of lipopolysaccharide (LPS)-induced inflammation in TH...

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Detalles Bibliográficos
Autores principales: Zhou, Chunlei, Zhao, Lan, Wang, Kai, Qi, Qianru, Wang, Meng, Yang, Lei, Sun, Ping, Mu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755493/
https://www.ncbi.nlm.nih.gov/pubmed/31572547
http://dx.doi.org/10.3892/etm.2019.7881