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Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies
Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44‐targeted inclusion bodies produced in recombinant bacteria. In this unusual particulate form, both types of protein materials selectively penetrate and kill CD44(+) tumor cells in culture, and upon lo...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755514/ https://www.ncbi.nlm.nih.gov/pubmed/31559131 http://dx.doi.org/10.1002/advs.201900849 |