Cargando…
Perampanel inhibits calcitonin gene-related peptide release from rat brainstem in vitro
BACKGROUND: Perampanel is a novel antiepileptic drug acting via non-competitive antagonism on glutamatergic AMPA receptors, and the subsequent inhibition of ion calcium influx. Since it was recently postulated that the antagonists of glutamate receptors might play a role in the treatment of migraine...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755590/ https://www.ncbi.nlm.nih.gov/pubmed/30419806 http://dx.doi.org/10.1186/s10194-018-0940-5 |