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Perampanel inhibits calcitonin gene-related peptide release from rat brainstem in vitro
BACKGROUND: Perampanel is a novel antiepileptic drug acting via non-competitive antagonism on glutamatergic AMPA receptors, and the subsequent inhibition of ion calcium influx. Since it was recently postulated that the antagonists of glutamate receptors might play a role in the treatment of migraine...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Milan
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755590/ https://www.ncbi.nlm.nih.gov/pubmed/30419806 http://dx.doi.org/10.1186/s10194-018-0940-5 |