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Interaction of HSD11B1 and H6PD polymorphisms in subjects with type 2 diabetes are protective factors against obesity: a cross-sectional study

BACKGROUND: The enzyme 11-beta hydroxysteroid dehydrogenase type 1 (HSD11B1) converts inactive cortisone to active cortisol in a process mediated by the enzyme hexose-6-phosphate dehydrogenase (H6PD). The generation of cortisol from this reaction may increase intra-abdominal cortisol levels and cont...

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Detalles Bibliográficos
Autores principales: Chedid, Marcio F., do Nascimento, Filipe V., de Oliveira, Fernanda S., de Souza, Bianca M., Kruel, Cleber R. P., Gurski, Richard R., Canani, Luis H., Crispim, Daisy, Gerchman, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755690/
https://www.ncbi.nlm.nih.gov/pubmed/31558916
http://dx.doi.org/10.1186/s13098-019-0474-2