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Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae

Neisseria gonorrhoeae responds to host-derived antimicrobials by inducing the expression of the mtrCDE-encoded multidrug efflux pump, which expels microbicides, such as bile salts, fatty acids, and multiple extrinsically administered drugs, from the cell. In the absence of these cytotoxins, the TetR...

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Detalles Bibliográficos
Autores principales:	Beggs, Grace A., Zalucki, Yaramah M., Brown, Nicholas Gene, Rastegari, Sheila, Phillips, Rebecca K., Palzkill, Timothy, Shafer, William M., Kumaraswami, Muthiah, Brennan, Richard G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755732/ https://www.ncbi.nlm.nih.gov/pubmed/31331979 http://dx.doi.org/10.1128/JB.00401-19

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