Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential

OBJECTIVE: To assess the phenotype of human articular chondrocytes cultured in normoxia (21% O(2)) or continuous hypoxia (2% O(2)). DESIGN: Chondrocytes were extracted from patients undergoing total knee replacement (n = 5) and cultured in ~21% (normoxic chondrocytes, NC) and 2% (hypoxic chondrocyte...

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Detalles Bibliográficos
Autores principales: Mennan, Claire, Garcia, John, McCarthy, Helen, Owen, Sharon, Perry, Jade, Wright, Karina, Banerjee, Robin, Richardson, James B., Roberts, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755872/
https://www.ncbi.nlm.nih.gov/pubmed/29671342
http://dx.doi.org/10.1177/1947603518769714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755872/
https://www.ncbi.nlm.nih.gov/pubmed/29671342
http://dx.doi.org/10.1177/1947603518769714

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