The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting

Perturbations to mammalian SWI/SNF (mSWI/SNF) chromatin remodeling complexes have been widely implicated as driving events in cancer(1). One such perturbation is the dual loss of the SMARCA4 and SMARCA2 ATPase subunits in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT)(2–5), SMARCA4-d...

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Detalles Bibliográficos
Autores principales: Pan, Joshua, McKenzie, Zachary M., D’Avino, Andrew R., Mashtalir, Nazar, Lareau, Caleb A., St. Pierre, Roodolph, Wang, Lu, Shilatifard, Ali, Kadoch, Cigall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755913/
https://www.ncbi.nlm.nih.gov/pubmed/30858614
http://dx.doi.org/10.1038/s41588-019-0363-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755913/
https://www.ncbi.nlm.nih.gov/pubmed/30858614
http://dx.doi.org/10.1038/s41588-019-0363-5

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