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Light-based control of metabolic flux through assembly of synthetic organelles

To maximize a desired product, metabolic engineers typically express enzymes to high, constant levels. Yet permanent pathway activation can have undesirable consequences including competition with essential pathways and accumulation of toxic intermediates. Faced with similar challenges, natural meta...

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Detalles Bibliográficos
Autores principales: Zhao, Evan M., Suek, Nathan, Wilson, Max Z., Dine, Elliot, Pannucci, Nicole L., Gitai, Zemer, Avalos, José L., Toettcher, Jared E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755918/
https://www.ncbi.nlm.nih.gov/pubmed/31086330
http://dx.doi.org/10.1038/s41589-019-0284-8