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Light-based control of metabolic flux through assembly of synthetic organelles
To maximize a desired product, metabolic engineers typically express enzymes to high, constant levels. Yet permanent pathway activation can have undesirable consequences including competition with essential pathways and accumulation of toxic intermediates. Faced with similar challenges, natural meta...
Autores principales: | Zhao, Evan M., Suek, Nathan, Wilson, Max Z., Dine, Elliot, Pannucci, Nicole L., Gitai, Zemer, Avalos, José L., Toettcher, Jared E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755918/ https://www.ncbi.nlm.nih.gov/pubmed/31086330 http://dx.doi.org/10.1038/s41589-019-0284-8 |
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