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Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL

As novel immunological treatments are gaining a foothold in the treatment of acute lymphoblastic leukemia (ALL), it is elemental to examine ALL immunobiology in more detail. We used multiplexed immunohistochemistry (mIHC) to study the immune contexture in adult precursor B cell ALL bone marrow (BM)....

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Detalles Bibliográficos
Autores principales: Hohtari, Helena, Brück, Oscar, Blom, Sami, Turkki, Riku, Sinisalo, Marjatta, Kovanen, Panu E., Kallioniemi, Olli, Pellinen, Teijo, Porkka, Kimmo, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755974/
https://www.ncbi.nlm.nih.gov/pubmed/30635636
http://dx.doi.org/10.1038/s41375-018-0360-1