Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia

Deregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway is found in cancer with STAT5A/B controlling leukemic cell survival and disease progression. As mutations in STAT5B, but not STAT5A, have been frequently described in hematopoietic tumors...

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Detalles Bibliográficos
Autores principales: Kollmann, Sebastian, Grundschober, Eva, Maurer, Barbara, Warsch, Wolfgang, Grausenburger, Reinhard, Edlinger, Leo, Huuhtanen, Jani, Lagger, Sabine, Hennighausen, Lothar, Valent, Peter, Decker, Thomas, Strobl, Birgit, Mueller, Mathias, Mustjoki, Satu, Hoelbl-Kovacic, Andrea, Sexl, Veronika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755975/
https://www.ncbi.nlm.nih.gov/pubmed/30679796
http://dx.doi.org/10.1038/s41375-018-0369-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755975/
https://www.ncbi.nlm.nih.gov/pubmed/30679796
http://dx.doi.org/10.1038/s41375-018-0369-5

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