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Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors

The molecular mechanisms leading to aryl hydrocarbon receptor interacting protein (AIP) mutation-induced aggressive, young-onset growth hormone-secreting pituitary tumors are not fully understood. In this study, we have identified that AIP-mutation-positive tumors are infiltrated by a large number o...

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Detalles Bibliográficos
Autores principales: Barry, Sayka, Carlsen, Eivind, Marques, Pedro, Stiles, Craig E., Gadaleta, Emanuela, Berney, Dan M., Roncaroli, Federico, Chelala, Claude, Solomou, Antonia, Herincs, Maria, Caimari, Francisca, Grossman, Ashley B., Crnogorac-Jurcevic, Tatjana, Haworth, Oliver, Gaston-Massuet, Carles, Korbonits, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755983/
https://www.ncbi.nlm.nih.gov/pubmed/30867568
http://dx.doi.org/10.1038/s41388-019-0779-5