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WNT signaling modulates PD-L1 expression in the stem cell compartment of triple-negative breast cancer

Triple-negative breast cancers (TNBCs) are characterized by a poor prognosis and lack of targeted treatments, and thus, new therapeutic strategies are urgently needed. Inhibitors against programmed death-1 (PD-1)/PD-1 ligand (PD-L1) have shown significant efficacy in various solid cancers, but their...

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Detalles Bibliográficos
Autores principales: Castagnoli, Lorenzo, Cancila, Valeria, Cordoba-Romero, Sandra L., Faraci, Simona, Talarico, Giovanna, Belmonte, Beatrice, Iorio, Marilena V., Milani, Matteo, Volpari, Tatiana, Chiodoni, Claudia, Hidalgo-Miranda, Alfredo, Tagliabue, Elda, Tripodo, Claudio, Sangaletti, Sabina, Di Nicola, Massimo, Pupa, Serenella M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755989/
https://www.ncbi.nlm.nih.gov/pubmed/30705400
http://dx.doi.org/10.1038/s41388-019-0700-2