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Conservation and divergence of the p53 gene regulatory network between mice and humans
Understanding the p53 tumor suppressor pathway remains crucial for the design of anticancer strategies. Studies in human tumors and mouse models help to unravel the molecular mechanisms that underlie the p53 signaling pathway. Yet, the p53 gene regulatory network (GRN) is not the same in mice and hu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755996/ https://www.ncbi.nlm.nih.gov/pubmed/30710145 http://dx.doi.org/10.1038/s41388-019-0706-9 |