Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration

Vimentin intermediate filaments (VIFs), expressed in most mesenchymal and cancer cells, undergo dramatic reorganization during cell migration; however, the mechanism remains obscure. This study demonstrates that upon growth-factor stimulation, Src directly phosphorylates vimentin at Tyr117, leading...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Yi, Chang, Po-Wei, Hsu, Wen-Hsin, Chang, Hsuan-Chia, Chen, Chien-Lin, Lai, Chien-Chen, Chiu, Wen-Tai, Chen, Hong-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755999/
https://www.ncbi.nlm.nih.gov/pubmed/30696956
http://dx.doi.org/10.1038/s41388-019-0705-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755999/
https://www.ncbi.nlm.nih.gov/pubmed/30696956
http://dx.doi.org/10.1038/s41388-019-0705-x

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