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The inflammatory cytokine IL-6 induces FRA1 deacetylation promoting colorectal cancer stem-like properties
Colorectal cancer (CRC) has long been known for its tight association with chronic inflammation, thought to play a key role in tumor onset and malignant progression through the modulation of cancer stemness. However, the underlying molecular and cellular mechanisms are still largely elusive. Here we...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756002/ https://www.ncbi.nlm.nih.gov/pubmed/30804456 http://dx.doi.org/10.1038/s41388-019-0763-0 |