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The inflammatory cytokine IL-6 induces FRA1 deacetylation promoting colorectal cancer stem-like properties

Colorectal cancer (CRC) has long been known for its tight association with chronic inflammation, thought to play a key role in tumor onset and malignant progression through the modulation of cancer stemness. However, the underlying molecular and cellular mechanisms are still largely elusive. Here we...

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Detalles Bibliográficos
Autores principales: Wang, Tingyang, Song, Ping, Zhong, Tingting, Wang, Xianjun, Xiang, Xueping, Liu, Qian, Chen, Haiyi, Xia, Tian, Liu, Hong, Niu, Yumiao, Hu, Yanshi, Xu, Lei, Shao, Yingkuan, Zhu, Lijun, Qi, Hongyan, Shen, Jing, Hou, Tingjun, Fodde, Riccardo, Shao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756002/
https://www.ncbi.nlm.nih.gov/pubmed/30804456
http://dx.doi.org/10.1038/s41388-019-0763-0