B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells

Cancer stem cells (CSCs) have been implicated in metastasis, relapse, and therapeutic resistance of cancer, so successful cancer therapy may therefore require the development of drugs against CSCs or combining anti-CSCs drugs with conventional therapies. The phosphoinositide 3-kinase (PI3K) signalin...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyu, Yu, Chunlei, Kong, Lingmei, Xu, Xiaoliang, Yan, Juming, Li, Yingchao, An, Tao, Gong, Liang, Gong, Yaxiao, Zhu, Huifang, Zhang, Hongbin, Yang, Xiaodong, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756013/
https://www.ncbi.nlm.nih.gov/pubmed/30635656
http://dx.doi.org/10.1038/s41388-018-0674-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756013/
https://www.ncbi.nlm.nih.gov/pubmed/30635656
http://dx.doi.org/10.1038/s41388-018-0674-5

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