Mono-ADP-ribosylation of H3R117 traps 5mC hydroxylase TET1 to impair demethylation of tumor suppressor gene TFPI2

Recently, nuclear poly-ADP-ribosylation had aroused research interest in epigenetics, but little attempt to explore functions of mono-ADP-ribosylation of histone, the major formation of histone ADP-ribosylated modification. We have previously reported a novel mono-ADP-ribosylation of H3R117, which p...

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Detalles Bibliográficos
Autores principales: Li, Ming, Tang, Yi, Li, Qingshu, Xiao, Ming, Yang, Yaying, Wang, Yalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756014/
https://www.ncbi.nlm.nih.gov/pubmed/30651599
http://dx.doi.org/10.1038/s41388-018-0671-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756014/
https://www.ncbi.nlm.nih.gov/pubmed/30651599
http://dx.doi.org/10.1038/s41388-018-0671-8

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