Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism

The Bcl-2-associated death promoter BAD is a prognostic indicator for good clinical outcome of breast cancer patients; however, whether BAD affects breast cancer biology is unknown. Here we showed that BAD increased cell growth in breast cancer cells through two distinct mechanisms. Phosphorylation...

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Detalles Bibliográficos
Autores principales: Mann, Jasdeep, Githaka, John Maringa, Buckland, Timothy W., Yang, Ning, Montpetit, Rachel, Patel, Namrata, Li, Lei, Baksh, Shairaz, Godbout, Roseline, Lemieux, Hélène, Goping, Ing Swie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756016/
https://www.ncbi.nlm.nih.gov/pubmed/30635657
http://dx.doi.org/10.1038/s41388-018-0673-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756016/
https://www.ncbi.nlm.nih.gov/pubmed/30635657
http://dx.doi.org/10.1038/s41388-018-0673-6

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