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Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma
The underlying forces that shape mutational patterns within any type of cancer have been poorly characterized. One of the best preserved exclusionary relationships is that between BRAF(V600E) and NRAS(Q61) in melanomas. To explore possible mechanisms which could explain this phenomenon, we overexpre...
Autores principales: | Kumar, Raj, Njauw, Ching-Ni, Reddy, Bobby Y., Ji, Zhenyu, Rajadurai, Anpuchchelvi, Klebanov, Nikolai, Tsao, Hensin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756020/ https://www.ncbi.nlm.nih.gov/pubmed/30651601 http://dx.doi.org/10.1038/s41388-018-0632-2 |
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