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EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation

Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using multi-step culture systems that reproduce the sequential cell differentiation occurring in vivo. Using this unique model, we investigated the role of EZH2...

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Detalles Bibliográficos
Autores principales: Herviou, Laurie, Jourdan, Michel, Martinez, Anne-Marie, Cavalli, Giacomo, Moreaux, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756037/
https://www.ncbi.nlm.nih.gov/pubmed/30755708
http://dx.doi.org/10.1038/s41375-019-0392-1