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EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation
Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using multi-step culture systems that reproduce the sequential cell differentiation occurring in vivo. Using this unique model, we investigated the role of EZH2...
Autores principales: | Herviou, Laurie, Jourdan, Michel, Martinez, Anne-Marie, Cavalli, Giacomo, Moreaux, Jerome |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756037/ https://www.ncbi.nlm.nih.gov/pubmed/30755708 http://dx.doi.org/10.1038/s41375-019-0392-1 |
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