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Dynamic m(6)A mRNA methylation reveals the role of METTL3-m(6)A-CDCP1 signaling axis in chemical carcinogenesis

N6-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNAs. Despite its functional importance in various physiological events, the role of m(6)A in chemical carcinogenesis remains largely unknown. Here we profiled the dynamic m(6)A mRNA modification during cellular tran...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Jin, Huan, Que, Biao, Chao, Yinghui, Zhang, Haiqing, Ying, Xiaoling, Zhou, Zhongyang, Yuan, Zusen, Su, Jialin, Wu, Bin, Zhang, Wenjuan, Qi, Defeng, Chen, Demeng, Min, Wang, Lin, Shuibin, Ji, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756049/
https://www.ncbi.nlm.nih.gov/pubmed/30796352
http://dx.doi.org/10.1038/s41388-019-0755-0