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Targeted killing of TNFR2-expressing tumor cells and T(regs) by TNFR2 antagonistic antibodies in advanced Sézary syndrome
Sézary syndrome (SS) is a rare form of cutaneous T-cell lymphoma often refractory to treatment. SS is defined as adenopathy, erythroderma with high numbers of atypical T cells. This offers an opportunity for new interventions and perhaps antibody-based therapeutic by virtue of its high expression of...
Autores principales: | Torrey, H, Khodadoust, M, Tran, L, Baum, D, Defusco, A, Kim, Y H, Faustman, D L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756055/ https://www.ncbi.nlm.nih.gov/pubmed/30356161 http://dx.doi.org/10.1038/s41375-018-0292-9 |
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