Cargando…

PKCζ facilitates lymphatic metastatic spread of prostate cancer cells in a mice xenograft model

Prostate cancer disseminates primarily into the adjacent lymph nodes, which is related to a poor outcome. Atypical protein kinase C ζ (PKCζ) is highly expressed in aggressive prostate cancer and correlates with Gleason score, clinical stage, and poor prognosis. Here, we report the molecular mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Zang, Guangxiang, Mu, Yabing, Gao, Linlin, Bergh, Anders, Landström, Marene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756056/
https://www.ncbi.nlm.nih.gov/pubmed/30705401
http://dx.doi.org/10.1038/s41388-019-0722-9