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TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila

Organ size is regulated by intercellular signaling for cell growth and proliferation. The TOR pathway mediates a key signaling mechanism for controlling cell size and number in organ growth. Chaperonin containing TCP-1 (CCT) is a complex that assists protein folding and function, but its role in ani...

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Detalles Bibliográficos
Autores principales: Kim, Ah-Ram, Choi, Kwang-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756063/
https://www.ncbi.nlm.nih.gov/pubmed/30792539
http://dx.doi.org/10.1038/s41388-019-0754-1