The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling

Inactivation of the tumor suppressor NF2/merlin underlies neurofibromatosis type 2 (NF2) and some sporadic tumors. Previous studies have established that merlin mediates contact inhibition of proliferation; however, the exact mechanisms remain obscure and multiple pathways have been implicated. We h...

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Detalles Bibliográficos
Autores principales: Cui, Yan, Groth, Susann, Troutman, Scott, Carlstedt, Annemarie, Sperka, Tobias, Riecken, Lars Björn, Kissil, Joseph L., Jin, Hongchuan, Morrison, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756068/
https://www.ncbi.nlm.nih.gov/pubmed/31312020
http://dx.doi.org/10.1038/s41388-019-0883-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756068/
https://www.ncbi.nlm.nih.gov/pubmed/31312020
http://dx.doi.org/10.1038/s41388-019-0883-6

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