Cargando…
Mechanisms underlying the activation of TERT transcription and telomerase activity in human cancer: old actors and new players
Long-lived species Homo sapiens have evolved robust protection mechanisms against cancer by repressing telomerase and maintaining short telomeres, thereby delaying the onset of the majority of cancer types until post-reproductive age. Indeed, telomerase is silent in most differentiated human cells,...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756069/ https://www.ncbi.nlm.nih.gov/pubmed/31285550 http://dx.doi.org/10.1038/s41388-019-0872-9 |