Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains

About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, particularly within the framework of clinically relevant molecular subtype...

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Detalles Bibliográficos
Autores principales: Berg, Kaja C. G., Sveen, Anita, Høland, Maren, Alagaratnam, Sharmini, Berg, Marianne, Danielsen, Stine A., Nesbakken, Arild, Søreide, Kjetil, Lothe, Ragnhild A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756070/
https://www.ncbi.nlm.nih.gov/pubmed/31308487
http://dx.doi.org/10.1038/s41388-019-0868-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756070/
https://www.ncbi.nlm.nih.gov/pubmed/31308487
http://dx.doi.org/10.1038/s41388-019-0868-5

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