Depletion of Ars2 inhibits cell proliferation and leukemogenesis in acute myeloid leukemia by modulating the miR-6734-3p/p27 axis

Ars2 is a component of the nuclear cap-binding complex (CBC) that contributes to microRNA biogenesis and is required for cellular proliferation. Little is known regarding the functional role of Ars2 in cell proliferation and leukemogenesis of acute myeloid leukemia. Here, we show that the elevated e...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoye, Xu, Shuangnian, Chen, Yibiao, Gao, Ziyi, Li, Yunong, Hu, Jinjiao, Huang, Xiuning, Zhang, Yanhao, Jiang, Xiuxing, Li, Lirong, Yang, Chong, Chen, Jieping, Gao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756072/
https://www.ncbi.nlm.nih.gov/pubmed/30518811
http://dx.doi.org/10.1038/s41375-018-0301-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756072/
https://www.ncbi.nlm.nih.gov/pubmed/30518811
http://dx.doi.org/10.1038/s41375-018-0301-z

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