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New role of P2X7 receptor in an Alzheimer’s disease mouse model

Extracellular aggregates of amyloid β (Aβ) peptides, which are characteristic of Alzheimer’s disease (AD), act as an essential trigger for glial cell activation and the release of ATP, leading to the stimulation of purinergic receptors, especially the P2X7 receptor (P2X7R). However, the involvement...

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Detalles Bibliográficos
Autores principales: Martin, Elodie, Amar, Majid, Dalle, Carine, Youssef, Ihsen, Boucher, Céline, Le Duigou, Caroline, Brückner, Matthias, Prigent, Annick, Sazdovitch, Véronique, Halle, Annett, Kanellopoulos, Jean M., Fontaine, Bertrand, Delatour, Benoît, Delarasse, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756107/
https://www.ncbi.nlm.nih.gov/pubmed/29934546
http://dx.doi.org/10.1038/s41380-018-0108-3