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MicroRNA 483-3p targets Pard3 to potentiate TGF-β1-induced cell migration, invasion, and epithelial–mesenchymal transition in anaplastic thyroid cancer cells

Anaplastic thyroid cancer (ATC) is associated with poor prognosis and is often untreatable. MicroRNA 483-3p (miR-483) and partitioning-defective 3 (Pard3), a member of the Pard family, have functions and regulatory mechanisms in ATC. The abnormal regulation of miR-483 may play an important role in t...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoping, Liu, Lin, Deng, Xianzhao, Li, Dan, Cai, Haidong, Ma, Yushui, Jia, Chengyou, Wu, Bo, Fan, Youben, Lv, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756112/
https://www.ncbi.nlm.nih.gov/pubmed/30171257
http://dx.doi.org/10.1038/s41388-018-0447-1