Antitumoral effects of attenuated Listeria monocytogenes in a genetically engineered mouse model of melanoma

Attenuated Listeria monocytogenes (Lm(at)-LLO) represents a valuable anticancer vaccine and drug delivery platform. Here we show that in vitro Lm(at)-LLO causes ROS production and, in turn, apoptotic killing of a wide variety of melanoma cells, irrespectively of their stage, mutational status, sensi...

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Detalles Bibliográficos
Autores principales: Vitiello, Marianna, Evangelista, Monica, Di Lascio, Nicole, Kusmic, Claudia, Massa, Annamaria, Orso, Francesca, Sarti, Samanta, Marranci, Andrea, Rodzik, Katarzyna, Germelli, Lorenzo, Chandra, Dinesh, Salvetti, Alessandra, Pucci, Angela, Taverna, Daniela, Faita, Francesco, Gravekamp, Claudia, Poliseno, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756113/
https://www.ncbi.nlm.nih.gov/pubmed/30664692
http://dx.doi.org/10.1038/s41388-019-0681-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756113/
https://www.ncbi.nlm.nih.gov/pubmed/30664692
http://dx.doi.org/10.1038/s41388-019-0681-1

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