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Histoepigenetic analysis of HPV- and tobacco-associated head and neck cancer identifies both subtype-specific and common therapeutic targets despite divergent microenvironments

Although head and neck squamous cell carcinoma (HNSCC) has in the past been largely associated with tobacco use, human papillomavirus (HPV+) oropharynx cancer has in recent years emerged as the fastest growing type of HNSCC. Patients with HPV+ HNSCC have a better prognosis; however, the 5-year survi...

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Detalles Bibliográficos
Autores principales: Carrero, Ivenise, Liu, Hsuan-Chen, Sikora, Andrew G., Milosavljevic, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756123/
https://www.ncbi.nlm.nih.gov/pubmed/30655605
http://dx.doi.org/10.1038/s41388-018-0659-4